HEATmarker®
Medical and pharmaceutical facilities, cold chain storage units risk undetected heat and temperature exposure over a period of time leading to cumulative degradation in the quality and potency of heat sensitive products. HEATmarker® supplied by Lisaline in India solves this cold chain problem completely.
What is HEATmarker® Time Temperature Indicator?
Temperature sensitive medical products undergo gradual, cumulative degradation from time-temperature exposure. HEATmarker® time temperature indicators are miniaturised, self-adhesive labels affixed by manufacturers to individual units and supplied by Lisaline as an official Zebra partner. They provide an irreversible visual signal of the extent of heat exposure over time.
How To Read Heat Indication in a HEATmarker® ?
The HEATmarker® time temperature indicator labels contain a square area of color-changing material (Active Surface) surrounded by a circle of fixed color (Figure 1).
When the color of the square matches or is darker than the circle, the HEATmarker® is indicating that the product has been exposed to potentially damaging heat.(Figure 2)
Key Features of HEATmarker®
- Time temperature indicator label colour changes gradually when exposed to heat over time.
- The rate of colour development is correlated to the heat stability of the product.
- Monitors heat exposure during storage and handling of products until the time of use.
- Signals if a specific temperature profile that may be damaging, has been reached.
Benefits of HEATmarker® Time Temperature Indicators
- Identify and avoid administration of potentially heat damaged medications to patients.
- Reduce unnecessary waste by limiting the destruction of products incorrectly suspected of heat overexposure.
- Enhance and support continual quality improvement.
- Extend quality control and risk management from production to patients.
HEATmarker® in Dot or Full
label Format
- HEATmarker® self‑adhesive time–temperature indicator label in a roll, designed for high‑speed application on automatic labeling machines.
- Applied easily on a variety of surfaces e.g. vials, flip off seal, prefill-syringes etc.
- Choice of more than 20 standard categories to meet the temperature stability profile of your product.
TransTracker® Card/ Label Format
- TransTracker® H, is a customized card/ self adhesive label with choice of HEATmarker® indicator.
- The card can be placed inside the multiple unit box.
- The self adhesive temperature indicator labels are fixed on the primary carton of pharmaceutical product, test kits etc.
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FAQs- HEATmarker®
What are the best time–temperature indicators for cold chain monitoring in India?
HEATmarker® time temperature indicators manufactured by Zebra and supplied by Lisaline Asia in India are among the best for cold chain monitoring. They provide an irreversible, cumulative visual signal of heat exposure on individual units. This helps ensure product integrity across the supply chain. Their miniaturized, self‑adhesive design and multiple temperature‑response profiles make them ideal for monitoring temperature‑sensitive medical products in real‑world Indian cold chain conditions.
How do HEATmarker® time temperature indicators work for pharmaceuticals?
HEATmarker® time–temperature indicators track heat exposure over time. They use a heat‑sensitive material that gradually and irreversibly darkens. When the inner square matches or becomes darker than the outer ring, it shows the product has reached its time–temperature limit. This helps identify if the pharmaceutical may have been exposed to potentially damaging heat during storage or transport.
Are HEATmarker® supplied by Lisaline single use disposable labels?
Yes. HEATmarker® indicators supplied by Lisaline are single‑use, disposable labels. They are self‑adhesive, miniaturised time–temperature indicators that provide an irreversible visual signal of heat exposure over the product’s shelf life and are not designed to be reused.
Which are the top companies providing time temperature indicator solutions in India?
Several companies in India supply time–temperature indicator solutions, including distributors of temperature‑sensitive labels for pharma and cold chain use. Lisaline Asia is the official supplier of HEATmarker® time–temperature indicators in India, which makes it one of the top companies providing ready‑to‑use time–temperature indicator labels for cold chain monitoring in the country.
What are time temperature indicators used for?
Time temperature indicators are used to monitor temperature‑sensitive pharmaceuticals (such as vaccines and biologics) during storage and transport. They provide a visual record of cumulative heat exposure, helping to verify cold‑chain integrity, support quality decisions, and reduce the risk of using degraded or ineffective medicines.
Why choose Lisaline as your HEATmarker® supplier in India?
Lisaline Asia is the official supplier of HEATmarker® time–temperature indicator labels in India and provides certified, licensed products that are safe and fully compliant. In a market where many unlicensed suppliers sell time temperature indicators, it becomes difficult to verify authenticity and product quality. Lisaline Asia helps overcome this challenge by offering genuine time temperature indicators along with complete technical support and a nationwide presence, making it a reliable and trusted partner for HEATmarker® labels across India.
How long does a HEATmarker® label remain active on a product?
A HEATmarker® label remains active for the duration of the product’s shelf life, continuously integrating time and temperature exposure until the color‑change endpoint is reached. The active life is matched to the product’s stability profile, so it gives a reliable visual signal of heat stress over the entire storage and transportation period.
What should users do if the HEATmarker® label shows a darkened color before expiry?
If the HEATmarker® label shows that the inner square has matched or become darker than the outer ring, it indicates that the product has reached its time–temperature endpoint and may have been exposed to damaging heat over a period of time affecting its potency.
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