bringing cold chain innovation

HEATmarker^®

Time-Temperature indicator for monitoring from Manufacturer
to Patient Administration.

What is HEATmarker^® Time Temperature Indicator?

The combined effects of time and temperature lead to the gradual and cumulative degradation of many temperature-sensitive medical products. HEATmarker® is a miniaturized, self-adhesive cumulative time-temperature indicator affixed by the manufacturer to individual units. It provides an irreversible visual signal that shows the extent of heat exposure over time.

How To Read Heat Indication

The HEATmarker® contains a square area of color-changing
material (Active Surface) surrounded by a circle of fixed color (Figure 1).

When the color of the square matches or is darker than the circle, the HEATmarker® is indicating that the product has been exposed to potentially damaging heat.(Figure 2)

Key Features

Indicator color changes gradually when exposed to heat over time.
The rate of color development is correlated to the heat stability of the product.
Monitors heat exposure during storage and handling of products until the time of use.
Signals if a specific temperature profile that may be damaging, has been reached.

Benefits of HEATmarker^®Indicators

Identify and avoid administration of potentially heat damaged medications to patients.
Reduce unnecessary waste by limiting the destruction of products incorrectly suspected of heat overexposure.
Enhance and support continual quality improvement.
Extend quality control and risk management from production to patients.