LIMITmarker®
clear, irreversible signal when exposure to a set
temperature occurs.
LIMITmarker F™ Indicator – Delayed Indication
LIMITmarker™ F is a threshold heat indicator with delayed indication. It is the most convenient device for monitoring product temperature during short term storage and shipments.
When LIMITmarker™ F indicators are exposed to temperatures at or above the response temperature, the window changes color to pink or red within the specified response time of 2 hours. The appearance of any pink or red in the window means that the indicator has reached “endpoint.”
LIMITmarker I™ Indicator – Immediate Indication
LIMITmarker™ I is a threshold heat indicator with immediate indication. It is the useful device for monitoring product temperature during short term storage and shipments.
LIMITmarker™ I, a high heat threshold indicator that monitors temperature and immediately indicates when the heat exposure, at or above the response temperature is exceeded. If the color of the centre circle matches or is darker than the outer circle, the ENDPOINT has been reached indicating that the predetermined threshold heat profile has been exceeded.
Use of LIMITmarker™ Indicators
LIMITmarker® with adhesive-backing, can be applied directly to product surfaces or packaging. Leading manufacturers and distributors use LIMITmarker™ heat indicators on temperature sensitive medical products.
- To ensure compliance with regulatory guidelines.
- To extend their quality systems into the distribution system.
- To communicate their commitment to cold chain best practices.
Types of Indicators
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Know More about Our HEATmarker® Time Temperature Indicator Labels
FAQs- HEATmarker®
What are the best time–temperature indicators for cold chain monitoring in India?
HEATmarker® time temperature indicators manufactured by Zebra and supplied by Lisaline Asia in India are among the best for cold chain monitoring. They provide an irreversible, cumulative visual signal of heat exposure on individual units. This helps ensure product integrity across the supply chain. Their miniaturized, self‑adhesive design and multiple temperature‑response profiles make them ideal for monitoring temperature‑sensitive medical products in real‑world Indian cold chain conditions.
How do HEATmarker® time temperature indicators work for pharmaceuticals?
HEATmarker® time–temperature indicators track heat exposure over time. They use a heat‑sensitive material that gradually and irreversibly darkens. When the inner square matches or becomes darker than the outer ring, it shows the product has reached its time–temperature limit. This helps identify if the pharmaceutical may have been exposed to potentially damaging heat during storage or transport.
Are HEATmarker® supplied by Lisaline single use disposable labels?
Yes. HEATmarker® indicators supplied by Lisaline are single‑use, disposable labels. They are self‑adhesive, miniaturised time–temperature indicators that provide an irreversible visual signal of heat exposure over the product’s shelf life and are not designed to be reused.
Which are the top companies providing time temperature indicator solutions in India?
Several companies in India supply time–temperature indicator solutions, including distributors of temperature‑sensitive labels for pharma and cold chain use. Lisaline Asia is the official supplier of HEATmarker® time–temperature indicators in India, which makes it one of the top companies providing ready‑to‑use time–temperature indicator labels for cold chain monitoring in the country.
What are time temperature indicators used for?
Time temperature indicators are used to monitor temperature‑sensitive pharmaceuticals (such as vaccines and biologics) during storage and transport. They provide a visual record of cumulative heat exposure, helping to verify cold‑chain integrity, support quality decisions, and reduce the risk of using degraded or ineffective medicines.
Why choose Lisaline as your HEATmarker® supplier in India?
Lisaline Asia is the official supplier of HEATmarker® time–temperature indicator labels in India and provides certified, licensed products that are safe and fully compliant. In a market where many unlicensed suppliers sell time temperature indicators, it becomes difficult to verify authenticity and product quality. Lisaline Asia helps overcome this challenge by offering genuine time temperature indicators along with complete technical support and a nationwide presence, making it a reliable and trusted partner for HEATmarker® labels across India.
How long does a HEATmarker® label remain active on a product?
A HEATmarker® label remains active for the duration of the product’s shelf life, continuously integrating time and temperature exposure until the color‑change endpoint is reached. The active life is matched to the product’s stability profile, so it gives a reliable visual signal of heat stress over the entire storage and transportation period.
What should users do if the HEATmarker® label shows a darkened color before expiry?
If the HEATmarker® label shows that the inner square has matched or become darker than the outer ring, it indicates that the product has reached its time–temperature endpoint and may have been exposed to damaging heat over a period of time affecting its potency.
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